Publications

From pCT

From Bergen Proton CT group

Published

  • Pettersen, H.E.S., J. Alme, A. van den Brink, M. Chaar, D. Fehlker, I. Meric, O.H. Odland, et al. Proton Tracking in a High-Granularity Digital Tracking Calorimeter for Proton CT Purposes. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 860C, 51–61. doi:10.1016/j.nima.2017.02.007.
  • Pettersen, H.E.S., Chaar, M., Meric, I., Odland, O.H., Sølie, J., Röhrich, D., n.d. Accuracy of parameterized proton range models; a comparison. doi:10.1016/j.radphyschem.2017.08.02

In review

  • J. Sølie, I. Meric and H. Pettersen: A comparison of longitudinal and lateral range for protons traversing complex media using GATE, MCNP6 and FLUKA Monte Carlo simulations.
    • Preliminary manuscript: PDF
    • Submitted to Rad. Chem. Phys. in conjunction with the IRRMA X conference.

Under construction

  • H. Pettersen, J. Sølie, I. Meric, D. Röhrich, O. H. Odland, etc.: Design optimization of a pixelated proton range telescope
    • Preliminary manuscript: PDF
    • This paper might be generalized somewhat for publication
  • H. Pettersen, I. Meric, O. H. Odland, H. Shafiee, J. Sølie, D. Röhrich: Reconstruction of Proton Tracks Inside a Digital Tracking Calorimeter for Proton Computed Tomography
    • To be submitted as part of the Connecting the Dots workshop proceedings, with deadline 2018-06-30.

Review articles on proton CT

  • G. Poludniowski, N.M. Allinson, P.M. Evans, Proton radiography and tomography with application to proton therapy, The British Journal of Radiology. 88 (2015) 20150134. doi:10.1259/bjr.20150134.
  • C. Civinini, Tracking for pCT - global status update, (2013).

Historical

  • K.M. Hanson, C.A. Taylor, M.A. Paciotti, R.J. Macek, D.B. Laubacher, R.L. Hutson, T.M. Cannon, J.N. Bradbury, Computed tomography using proton energy loss, Physics in Medicine and Biology. 26 (1981) 965.
  • M. Urie, M. Goitein, W.R. Holley, G.T. Chen, Degradation of the Bragg peak due to inhomogeneities, Physics in Medicine and Biology. 31 (1986) 1.
  • K.M. Hanson, J.N. Bradbury, R.A. Koeppe, R.J. Macek, D.R. Machen, R. Morgado, M.A. Paciotti, S.A. Sandford, V.W. Steward, Proton computed tomography of human specimens, Physics in Medicine and Biology. 27 (1982) 25.
  • A.M. Koehler, Proton Radiography, Science. 160 (1968) 303–304.
  • M. Gotein, The measurement of tissue heterodensity to guide charged particle radiotherapy, International Journal of Radiation Oncology Biological Physics. 3 (1977) 27–33.
  • B. Schaffner, E. Pedroni, The precision of proton range calculations in proton radiotherapy treatment planning: experimental verification of the relation between CT-HU and proton stopping power, Physics in Medicine and Biology. 43 (1998) 1579.
  • H.F.-W. Sadrozinski, V. Bashkirov, B. Keeney, L.R. Johnson, S.G. Peggs, G. Ross, T. Satogata, R.W.M. Schulte, A. Seiden, K. Shanazi, D.C. Williams, Toward Proton Computed Tomography, IEEE Transactions on Nuclear Science. 51 (2004) 3–9. doi:10.1109/TNS.2003.823044.

On proton CT reconstruction with some novel approaches

  • R. Rescigno, C. Bopp, M. Rousseau, D. Brasse, A pencil beam approach to proton computed tomography, Medical Physics. 42 (2015) 6610–6624. doi:10.1118/1.4933422.
  • C.T. Quiñones, J.M. Létang, S. Rit, Filtered back-projection reconstruction for attenuation proton CT along most likely paths, Physics in Medicine and Biology. 61 (2016) 3258–3278. doi:10.1088/0031-9155/61/9/3258.
  • C. Bopp, J. Colin, D. Cussol, C. Finck, M. Labalme, M. Rousseau, D. Brasse, Proton computed tomography from multiple physics processes, Physics in Medicine and Biology. 58 (2013) 7261–7276. doi:10.1088/0031-9155/58/20/7261.
  • M. Bruzzi, N. Blumenkrantz, J. Feldt, J. Heimann, H.F.-W. Sadrozinski, A. Seiden, D.C. Williams, V. Bashkirov, R. Schulte, D. Menichelli, M. Scaringella, G.A.P. Cirrone, G. Cuttone, N. Randazzo, V. Sipala, D. Lo Presti, Prototype Tracking Studies for Proton CT, IEEE Transactions on Nuclear Science. 54 (2007) 140–145. doi:10.1109/TNS.2006.889642.
  • C. Bopp, R. Rescigno, M. Rousseau, D. Brasse, Quantitative proton imaging from multiple physics processes: a proof of concept, Physics in Medicine and Biology. 60 (2015) 5325–5341. doi:10.1088/0031-9155/60/13/5325.
  • C. Bopp, R. Rescigno, M. Rousseau, D. Brasse, The impact of tracking system properties on the most likely path estimation in proton CT, Physics in Medicine and Biology. 59 (2014) N197–N210. doi:10.1088/0031-9155/59/23/N197.

Publications on proton CT sorted by group

From PRaVDA

  • M. Esposito, T. Anaxagoras, P.M. Evans, S. Green, S. Manolopoulos, J. Nieto-Camero, D.J. Parker, G. Poludniowski, T. Price, C. Waltham, N.M. Allinson, CMOS Active Pixel Sensors as energy-range detectors for proton Computed Tomography, Journal of Instrumentation. 10 (2015) C06001–C06001. doi:10.1088/1748-0221/10/06/C06001.
  • M. Esposito, T. Anaxagoras, A. Fant, K. Wells, A. Konstantinidis, J.P.F. Osmond, P.M. Evans, R.D. Speller, N.M. Allinson, DynAMITe: a wafer scale sensor for biomedical applications, Journal of Instrumentation. 6 (2011) C12064–C12064. doi:10.1088/1748-0221/6/12/C12064.
  • T. Price, M. Esposito, G. Poludniowski, J. Taylor, C. Waltham, D.J. Parker, S. Green, S. Manolopoulos, N.M. Allinson, T. Anaxagoras, P. Evans, J. Nieto-Camero, Expected proton signal sizes in the PRaVDA Range Telescope for proton Computed Tomography, Journal of Instrumentation. 10 (2015) P05013–P05013. doi:10.1088/1748-0221/10/05/P05013.
  • G. Poludniowski, N.M. Allinson, P.M. Evans, Proton computed tomography reconstruction using a backprojection-then-filtering approach, Physics in Medicine and Biology. 59 (2014) 7905–7918. doi:10.1088/0031-9155/59/24/7905.
  • G. Poludniowski, N.M. Allinson, T. Anaxagoras, M. Esposito, S. Green, S. Manolopoulos, J. Nieto-Camero, D.J. Parker, T. Price, P.M. Evans, Proton-counting radiography for proton therapy: a proof of principle using CMOS APS technology, Physics in Medicine and Biology. 59 (2014) 2569–2581. doi:10.1088/0031-9155/59/11/2569.

From Lomda Linda

  • T. Plautz, V. Bashkirov, V. Feng, F. Hurley, R.P. Johnson, C. Leary, S. Macafee, A. Plumb, V. Rykalin, H.F.-W. Sadrozinski, K. Schubert, R. Schulte, B. Schultze, D. Steinberg, M. Witt, A. Zatserklyaniy, 200 MeV Proton Radiography Studies With a Hand Phantom Using a Prototype Proton CT Scanner, IEEE Transactions on Medical Imaging. 33 (2014) 875–881. doi:10.1109/TMI.2013.2297278.
  • R. P. Johnson, V. Bashkirov, L. DeWitt, V. Giacometti, R. F. Hurley, P. Piersimoni, T. E. Plautz, H. F. W. Sadrozinski, K. Schubert, R. Schulte, B. Schultze, A. Zatserklyaniy, A Fast Experimental Scanner for Proton CT: Technical Performance and First Experience With Phantom Scans, IEEE Transactions on Nuclear Science. 63 (2016) 52–60. doi:10.1109/TNS.2015.2491918.
  • R. Schulte, V. Bashkirov, T. Li, Z. Liang, K. Mueller, J. Heimann, L.R. Johnson, B. Keeney, H.-W. Sadrozinski, A. Seiden, others, Conceptual design of a proton computed tomography system for applications in proton radiation therapy, Nuclear Science, IEEE Transactions on. 51 (2004) 866–872.
  • H.-W. Sadrozinski, R.P. Johnson, S. Macafee, A. Plumb, D. Steinberg, A. Zatserklyaniy, V.A. Bashkirov, R.F. Hurley, R.W. Schulte, Development of a head scanner for proton CT, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 699 (2013) 205–210.
  • H.-W. Sadrozinski, V. Bashkirov, M. Bruzzi, L.R. Johnson, B. Keeney, G. Ross, R.W. Schulte, A. Seiden, K. Shahnazi, D.C. Williams, others, Issues in proton computed tomography, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 511 (2003) 275–281.
  • R.W. Schulte, A.J. Wroe, New developments in treatment planning and verification of particle beam therapy, Translational Cancer Research. 1 (2012) 184–195.
  • V.A. Bashkirov, R.W. Schulte, R.F. Hurley, R.P. Johnson, H.F.-W. Sadrozinski, A. Zatserklyaniy, T. Plautz, V. Giacometti, Novel scintillation detector design and performance for proton radiography and computed tomography, Medical Physics. 43 (2016) 664–674. doi:10.1118/1.4939255.
  • R.W. Schulte, V. Bashkirov, R. Johnson, H.-W. Sadrozinski, K.E. Schubert, Overview of the LLUMC/UCSC/CSUSB Phase 2 Proton CT Project, Transactions of the American Nuclear Society. 106 (2012) 59.
  • R. Johnson, V.A. Bashkirov, V. Giacometti, R.F. Hurley, P. Piersimoni, T. Plautz, Results from a pre-clinical head scanner for proton CT, (2014).
  • R.F. Hurley, R.W. Schulte, V.A. Bashkirov, G. Coutrakon, H.-W. Sadrozinski, B. Patyal, The Phase I Proton CT Scanner and Test Beam Results at LLUMC, invited, Transactions of the American Nuclear Society. 106 (2012) 63.
  • R.P. Johnson, J. DeWitt, C. Holcomb, S. Macafee, H.F.-W. Sadrozinski, D. Steinberg, Tracker Readout ASIC for Proton Computed Tomography Data Acquisition, IEEE Transactions on Nuclear Science. 60 (2013) 3262–3269. doi:10.1109/TNS.2013.2274663.
  • R.F. Hurley, R.W. Schulte, V.A. Bashkirov, A.J. Wroe, A. Ghebremedhin, H.F.-W. Sadrozinski, V. Rykalin, G. Coutrakon, P. Koss, B. Patyal, Water-equivalent path length calibration of a prototype proton CT scanner, Medical Physics. 39 (2012) 2438. doi:10.1118/1.3700173.

From the NIU project (using scitillating fibres)

  • M. Naimuddin, G. Coutrakon, G. Blazey, S. Boi, A. Dyshkant, B. Erdelyi, D. Hedin, E. Johnson, J. Krider, V. Rukalin, others, Development of a proton Computed Tomography detector system, Journal of Instrumentation. 11 (2016) C02012.
  • S.A. Uzunyan, G. Blazey, S. Boi, G. Coutrakon, A. Dyshkant, B. Erdelyi, A. Gearhart, D. Hedin, E. Johnson, J. Krider, others, Development of a proton Computed Tomography (pCT) scanner at NIU, arXiv Preprint arXiv:1312.3977. (2013). http://arxiv.org/abs/1312.3977 (accessed January 15, 2015).

From the PRIMA project at INFN

  • M. Scaringella, M. Bruzzi, M. Bucciolini, M. Carpinelli, G.A.P. Cirrone, C. Civinini, G. Cuttone, D.L. Presti, S. Pallotta, C. Pugliatti, N. Randazzo, F. Romano, V. Sipala, C. Stancampiano, C. Talamonti, E. Vanzi, M. Zani, A proton Computed Tomography based medical imaging system, Journal of Instrumentation. 9 (2014) C12009–C12009. doi:10.1088/1748-0221/9/12/C12009.
  • C. Civinini, M. Bruzzi, M. Bucciolini, M. Carpinelli, G.A.P. Cirrone, G. Cuttone, D. Lo Presti, S. Pallotta, C. Pugliatti, N. Randazzo, others, Recent results on the development of a proton computed tomography system, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 732 (2013) 573–576.
  • E. Vanzi, M. Bruzzi, M. Bucciolini, G.A.P. Cirrone, C. Civinini, G. Cuttone, D. Lo Presti, S. Pallotta, C. Pugliatti, N. Randazzo, F. Romano, M. Scaringella, V. Sipala, C. Stancampiano, C. Talamonti, M. Zani, The PRIMA collaboration: Preliminary results in FBP reconstruction of pCT data, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 730 (2013) 184–190. doi:10.1016/j.nima.2013.05.193.
  • M. Scaringella, M. Brianzi, M. Bruzzi, M. Bucciolini, M. Carpinelli, G.A.P. Cirrone, C. Civinini, G. Cuttone, D. Lo Presti, S. Pallotta, others, The PRIMA (Proton Imaging) collaboration: development of a proton Computed Tomography apparatus, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 730 (2013) 178–183.
  • V. Sipala, N. Randazzo, D.L. Presti, C. Stancampiano, M. Bruzzi, M. Bucciolini, S. Pallotta, M. Scaringella, C. Talamonti, M. Tesi, others, Upgrade of the proton Computed Tomography system of the PRIMA project, PoS (RD11). 13 (2011). http://www.researchgate.net/publication/230709286_Upgrade_of_the_proton_Computed_Tomography_system_of_the_PRIMA_project_Speaker/file/9fcfd5034f8b703175.pdf (accessed January 15, 2015).

From the proton radiography project at Heidelberg

  • I. Rinaldi, S. Brons, O. Jäkel, B. Voss, K. Parodi, A method to increase the nominal range resolution of a stack of parallel-plate ionization chambers, Physics in Medicine and Biology. 59 (2014) 5501–5515. doi:10.1088/0031-9155/59/18/5501.
  • C. Kurz, A. Mairani, K. Parodi, First experimental-based characterization of oxygen ion beam depth dose distributions at the Heidelberg Ion-Beam Therapy Center, Physics in Medicine and Biology. 57 (2012) 5017–5034. doi:10.1088/0031-9155/57/15/5017.

(Historical) proton radiography at PSI

  • P. Pemler, J. Besserer, J. De Boer, M. Dellert, C. Gahn, M. Moosburger, U. Schneider, E. Pedroni, H. Stäuble, A detector system for proton radiography on the gantry of the Paul-Scherrer-Institute, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 432 (1999) 483–495.
  • N.S.P. King, E. Ables, K. Adams, K.R. Alrick, J.F. Amann, S. Balzar, P.D. Barnes Jr, M.L. Crow, S.B. Cushing, J.C. Eddleman, others, An 800-MeV proton radiography facility for dynamic experiments, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 424 (1999) 84–91.
  • S. Braccini, A. Ereditato, I. Kreslo, U. Moser, C. Pistillo, S. Studer, P. Scampoli, A. Coray, E. Pedroni, First results on proton radiography with nuclear emulsion detectors, Journal of Instrumentation. 5 (2010) P09001.
  • S. Braccini, A. Ereditato, I. Kreslo, U. Moser, C. Pistillo, P. Scampoli, S. Studer, Nuclear Emulsion Film Detectors for Proton Radiography: Design and Test of the First Prototype, arXiv Preprint arXiv:1001.0857. (2010). http://arxiv.org/abs/1001.0857 (accessed January 15, 2015).

Interesting theses on proton CT

  • P.C. Tsopelas, Applying GridPix as 3D particle tracker for proton radiography, MSc, University of Utrecht, 2011. https://wiki.nikhef.nl/detector/pub/Main/ArticlesAndTalks/Panagiotis_Tsopelas_Master_Thesis.pdf (accessed January 12, 2015).
  • E. Hansen, Charge diffusion modelling for a monolithic active pixel sensor detector with application to proton CT, BSc Project work, NTNU, 2016.
  • M. Yang, Dual Energy computed tomography for proton therapy treatment planning, PhD, University of Texas, 2011.
  • S.N. Penfold, Image reconstruction and Monte Carlo simulations in the development of proton computed tomography for applications in proton radiation therpy, PhD, University of Wollongong, 2010.
  • D.C. Hansen, Improving Ion Computed Tomography, PhD, Aarhus Universitet, 2014. http://pure.au.dk/portal/files/83515131/dissertation.pdf (accessed January 12, 2015).
  • L. Maczewski, Measurements and simulations of MAPS (Monolithic Active Pixel Sensors) response to charged particles - a study towards a vertex detector at the ILC, PhD, 2010. http://arxiv.org/abs/1005.3710 (accessed January 12, 2015).

On the ALPIDE chip

  • M. Mager, ALPIDE, the Monolithic Active Pixel Sensor for the ALICE ITS upgrade, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 824 (2016) 434–438. doi:10.1016/j.nima.2015.09.057.
  • C. Cavicchioli, P.L. Chalmet, P. Giubilato, H. Hillemanns, A. Junique, T. Kugathasan, M. Mager, C.A. Marin Tobon, P. Martinengo, S. Mattiazzo, H. Mugnier, L. Musa, D. Pantano, J. Rousset, F. Reidt, P. Riedler, W. Snoeys, J.W. Van Hoorne, P. Yang, Design and characterization of novel monolithic pixel sensors for the ALICE ITS upgrade, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 765 (2014) 177–182. doi:10.1016/j.nima.2014.05.027.
  • G. Aglieri Rinella, The ALPIDE pixel sensor chip for the upgrade of the ALICE Inner Tracking System, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. (2016). doi:10.1016/j.nima.2016.05.016.
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